Electroencephalogram signatures of ketamine anesthesia-induced unconsciousness
نویسندگان
چکیده
منابع مشابه
Neural mechanisms of ketamine-induced anesthesia.
The sites of action of ketamine (CI-581 ; 2-(0-chlorophenyl)-2-methylamino cyclo-hexamine HCI) were determined in the central nervous system using electrophysiological techniques in both acute and chronic cat experiments. It was demonstrated in chronic preparations that the cataleptic anesthetic state induced by ketamine is accompanied by an alternating pattern of hypersynchronous delta wave bu...
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The widely used electroencephalogram-based indices for depth-of-anesthesia monitoring assume that the same index value defines the same level of unconsciousness for all anesthetics. In contrast, we show that different anesthetics act at different molecular targets and neural circuits to produce distinct brain states that are readily visible in the electroencephalogram. We present a two-part rev...
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Nitric oxide (NO) is thought to be involved in spatial learning and memory in several brain areas such as hippocampus. This study examined the effects of post-training intrahippocampal microinjections of 1400W as a selective iNOS inhibitor on spatial memory, in anesthetized and non-anesthetized situations in rats. In the present work, 4-day training trials of animals were conducted. Spatial mem...
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Nitric oxide (NO) is thought to be involved in spatial learning and memory in several brain areas such as hippocampus. This study examined the effects of post-training intrahippocampal microinjections of 1400W as a selective iNOS inhibitor on spatial memory, in anesthetized and non-anesthetized situations in rats. In the present work, 4-day training trials of animals were conducted. Spatial mem...
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Important information about the state dynamics of the brain during anesthesia is unraveled by Electroencephalogram (EEG) approaches. Patterns that are observed through EEG related to neural circuit mechanism under different molecular targets dependent anesthetics have recently attracted much attention. Propofol, a Gamma-amino butyric acid, is known with evidently increasing alpha oscillation. D...
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ژورنال
عنوان ژورنال: Clinical Neurophysiology
سال: 2016
ISSN: 1388-2457
DOI: 10.1016/j.clinph.2016.03.005